Fertility and Pregnancy Rapid Test Kits Market Outlook and Forecast up to 2025

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Human chorionic gonadotropin (hCG) hormone, luteinizing hormone (LH), and follicle stimulating hormone (FSH) are some of the reproductive hormones which are quantitatively detected using the tools of fertility along with pregnancy rapid test kits. In males, the detection of the sperm count can be done with the use of fertility rapid test kits. In females, the fertility rapid test kits are used to confirm menopause or to find the exact day of ovulation. Immunoassay techniques which change the color are used in these devices, the type of the device being used decides which sample should be used for the test, whether blood or urine sample, a small quantity of sample is used for the test.

Increasing incidence of gynecological disorders and infertility and fast and self-contained tests are some of the driving factors for the growth of the global fertility and pregnancy rapid test kits market. Rise in first-time pregnancy age and availability of less time-consuming decentralized diagnostic tests in place of laboratory tests have boosted the market growth. Increasing inclination toward the smartphone app connectivity, attractive product features, and technological advancements have led to the adoption of fertility and pregnancy rapid test kits. These factors are boosting the demand for these devices and the market is projected to grow significantly during the forecast period. However, the impeding growth factors in countries who have inherent potential due to which these products are not well adopted, too many options in the market being available and controversies and issues related to the devices lead to the restraints of the growing market for fertility as well as pregnancy rapid test kits.

In Asia Pacific and Europe, the premier companies consolidate their position with strong local companies by maintaining distribution agreements and with e-commerce partners the strategies like creating alliances are employed in the market for fertility including pregnancy rapid test kits.

On the basis of product type, the market can be segmented as fertility rapid test kits and pregnancy rapid test kits. The pregnancy rapid test kits segment can be further classified as digital devices and line-indicator devices. The line-indicator devices includes mid-stream devices, strip/dip sticks, and cassettes. The fertility rapid test kits segment can be categorized as digital devices and line-indicators. On the basis of test type, the market can be segmented as hCG urine test, hCG blood test, FSH urine test, and LH urine test. Globally, there is a high prevalence of infertility rate and gynecological disorders leading to high demand for hCG rapid test. Based on distribution channel, the market can be segmented as fertility and gynecology clinics, hypermarkets and supermarkets, online sales, drugstores, pharmacies, and other clinics. The drugstores segment is the most preferable distribution channel, followed by the pharmacies segment. However, in some regions such as North America and Europe, these traditional distribution channels have started facing significant competition from the online sales segment due to increasing consumer preference toward online sales that provide doorstep services.

Geographically, the market for fertility and pregnancy rapid test kits is distributed over North America, Europe, Asia Pacific, and rest of the world. North America dominates the global market with the U.S. accounting for a considerable market share. Europe followed North America in terms of market share. The Asia Pacific and rest of the world markets are projected to expand at significant growth rate during the forecast period attributed to factors such as high unmet needs, emerging economies, and continuously improving scenario.

Prominent players operating in the fertility and pregnancy rapid test kits market include Quidel Corporation; Alere Inc.; Church & Dwight Co., Inc.; Prestige Brands Holdings, Inc.; Geratherm Medical AG; bioMérieux SA; Procter & Gamble Co.; Abbott Laboratories; Swiss Precision Diagnostics GmbH; and DCC Plc.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Huntington’s Disease Therapeutics Market: Aggressive Research Activities Stimulating Market Growth

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Huntington’s disease (HD) is an autosomal dominant hereditary disorder of the central nervous system. The disease results in progressive degeneration of the brain cells. A physician named George Huntington described the disorder in detail as hereditary chorea in 1872. Thus, earlier it was known as Huntington’s chorea or HC. Huntington’s disease usually develops symptoms in adulthood between the age of 30 years and 40 years. In case the symptoms of the disease are developed before the age of 20 years, it is referred as juvenile Huntington’s disease. Both men and women are susceptible to this disease. Studies show that one in every 10,000 people in America has HD and more than 250,000 people are at risk of inheriting the disease from a parent.

The disease causes a wide range of symptoms in an affected person. Primarily, it leads to difficulty in motor control (movement), cognition (thinking), and behavior. Motor problems include impairments in voluntary movements as well as onset of uncontrolled involuntary jerking. People suffering from HD also have muscle problems such as muscle contracture (dystonia) or rigidity, impaired gait, posture, and balance. Loss of motor control hampers a person’s daily activities and causes difficulty in living a normal life. The disease also leads to speech and swallowing problems (dysphagia). These occur when the centers of the motor or cognitive control responsible for these functions are affected. A significant behavior and cognition disorder associated with Huntington’s disease is depression that results due to brain injury and loss of brain function.

Although medical science has no cure for this disease, the symptoms of this disease can be detected and treated. Drugs to treat movement disorders include tetrabenazine (Xenazine), antipsychotic drugs such as haloperidol (Haldol), chlorpromazine, and others. Antidepressants such as escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), citalopram (Celexa), and sertraline (Zoloft) are given as treatment. Development in scientific research has led to increased awareness about Huntington’s disease. This is one of the key drivers for the growth of the Huntington’s disease therapeutics market. In addition, increased prevalence of the disease is a key growth driver of the market. Unmet medical needs have driven scientists and researchers to develop therapy for Huntington’s disease, which in turn is likely to drive the global market. Increased investment by many pharmaceutical companies in the research and development sector to develop innovative and curative drugs for the disease is driving the growth of the global market. Further, alternative therapies, including speech therapy, psychotherapy, and physiotherapy, increase the potential of the market growth for Huntington’s disease therapeutics.

Geographically, the global Huntington’s disease therapeutics market is distributed over North America, Europe, APAC, and Latin America. North America dominates the global market due to increased awareness about the disease. In the North America market, the U.S. holds the largest market share, followed by Canada. Europe accounts for the second largest market globally. In Europe, countries such as France, Germany, the U.K., and Spain contribute major shares of the market. Increasing awareness about the disease along with growing infrastructure for scientific research is projected to lead to market establishment for Huntington’s disease therapeutics in other parts of the world such as China, India, Japan, Africa, Argentina, and Brazil.

Key players contributing highest market shares include Teva Pharmaceutical Industries, Alnylam Pharmaceuticals, Inc., AmpliPhi Biosciences Corp, Pfizer, Lundbeck, Prana Biotechnology Ltd., Valeant Pharmaceuticals International Inc., Cortex Pharmaceuticals Inc., Vertex Pharmaceuticals Incorporated, GlaxoSmithKline, Auspex Pharmaceuticals, Ceregene Inc., SOM Biotech, Siena Biotech, Raptor Pharmaceutical, Palobiofarma, and Ipsen.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Mucopolysaccharidosis II (MPS II)/ Hunter Syndrome Market: An Overview of Growth Factors

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Mucopolysaccharidosis II (MPS II)/ Hunter syndrome is a congenital condition which leads to complications in carbohydrate metabolism. The first individual with X-linked Mucopolysaccharidosis (MPS) was first reported in 1917 by a clinician named Hunter. Hunter syndrome is known to occur almost exclusively in males and is characterized by distinctive facial features such as puffy lips, a large head, large rounded cheeks, a broad nose, and an enlarged tongue (macroglossia). Mucopolysaccharidosis II (MPS II)/ Hunter syndrome is caused by mutations in the IDS (iduronate 2-sulfatase) gene and is inherited in an X-linked manner. Hunter syndrome is a complex debilitating disease that leads to various anatomical and physiological anomalies with increasing age.

At birth, individuals with MPS II do not display any features of the condition. But with increasing age, the patient develops the above mentioned conditions. Moreover, the vocal cords also expand, which leads to a deep, hoarse voice. An enlarged tongue (macroglossia) and narrowing of the trachea results in upper respiratory infections and sleep apnea. As the syndrome develops, patients need medical assistance to keep their airway open. Patients with this disorder often develop an enlarged liver and spleen (hepatosplenomegaly), a large head (macrocephaly) and fluid buildup in the brain (hydrocephalus), umbilical hernia or lower abdomen hernia (inguinal hernia). The patients additionally have joint deformities and heart defects including the valves. Most individuals also develop hearing loss and have recurring ear infections. The patient also faces difficulties with the retina and has reduced vision. The effects on other bone joints, such as hips and knees, can lead to increased difficulties in walking normally. Hunter syndrome can also lead to development of carpal tunnel syndrome in young children resulting in a further decrease in hand function. The effect on bones results in short stature. Furthermore, pebbly, white skin lesions can be seen on the upper arms, legs, and back of some individuals with Hunter syndrome. The level and severity of progression is different for every individual with Hunter syndrome.

Although Hunter syndrome is associated with a wide range in severity of symptoms present in individuals, it has been classified as severe and mild/attenuated. The differences between the severe and attenuated forms are mainly characterized by the progressive development of neurodegeneration in the severe form. Hunter syndrome is a rare disorder affecting 1 in 100,000 to 1 in 150,000 males. As per an estimate 1 in 25,000 births result in some form of MPS in the United States. The obvious symptoms and signs of Hunter syndrome (MPS II) in younger people are typically the first indications leading to a diagnosis. A variety of diagnostic tests can be done to determine the presence of Hunter syndrome in an individual including genetic testing, and iduronate-2-sulfatase (I2S) enzyme activity test. The most frequently used laboratory screening test for an MPS disorder is a urine test for GAGs. It is important to note that a child can be suffering from an MPS syndrome and the urine test for GAG can still show normal results. A decisive diagnosis of Hunter syndrome can be done by determining I2S activity in white blood cells, serum, or fibroblasts from skin biopsy. Hunter syndrome can also be preventively detected effectively by prenatal diagnosis of I2S enzymatic activity in amniotic fluid.

The treatment regime for Hunter syndrome is determined depending on the severity of the symptoms and varies from patient to patient and on a case to case basis. Since there is no permanent cure for Hunter syndrome, the treatment mainly focuses on management of signs, indications, and complications associated with the disease progression. Palliative care is given to manage various conditions such as addressing heart complications, relief for respiratory complications, managing behavioral and neurological complications, addressing sleep issues, and treatment for skeletal and connective tissue problems. Some novel treatment approaches such as enzyme and gene therapy that are in early phases of development have helped in slowing the disease’s progress and lessening its severity, making the Mucopolysaccharidosis II (MPS II)/ Hunter syndrome treatment market a promising avenue for research and development.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Paraneoplastic Pemphigus Disease Market: An Overview of Growth Factors

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Paraneoplastic pemphigus is an autoimmune disease characterized by the formation of blisters that affect the mucous membranes and / or skin. It falls under the “rare diseases” category and can affect both males and females. According to Ophanet, paraneoplastic pemphigus affects 1 in 2,000 people. It is a rare form of pemphigus usually associated with lymph proliferative disorders such as Castleman disease, chronic lymphocytic leukemia, and non-Hodgkin’s lymphoma. Paraneoplastic pemphigus is a highly serious and rare form of pemphigus, especially due to the underlying malignancy in affected individuals. Its symptoms include respiratory, skin, oral, and other lesions. To diagnose paraneoplastic pemphigus, a blood test is generally carried out to check for the presence of IgG antibodies. After this, signs such as concurrent internal tumor, polymorphic mucocutaneous eruption, and serum antibodies with a specific immunoprecipitation pattern which indicate paraneoplastic pemphigus are checked for. There is no specific treatment for the pemphigus other than supportive measures such as attending to secondary infections and pain management. However, immunomodulators and immunosuppressive agents may be employed.

Factors such as the growing global prevalence of cancer, increasing consumption of tobacco, rising awareness, and unhealthy lifestyles drive the global paraneoplastic pemphigus (PNP) disease market. The rising health care expenditures, favorable insurance coverage, and increasing number of research & development activities are a few more propellants of the global paraneoplastic pemphigus (PNP) disease market. On the other hand, lack of awareness and stringent regulations may hinder the market.

The paraneoplastic pemphigus (PNP) disease market has been segmented by product type into the following categories: immunosuppresants and immunomodulators. The former include prednisolone, azathiprion, cyclosporin, and cyclophosphamide. The latter include gammagard, gamimune, and sandoglobulin. In terms of distribution channel, the paraneoplastic pemphigus (PNP) disease market is divided into the following sections: hospital pharmacies, retail pharmacies, and online pharmacies.

Geographically, the paraneoplastic pemphigus (PNP) disease market is distributed over North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Geographically, North America dominated the market due to the increasing geriatric population, technological advancements, and strong research & development activities in the region. Adults between the ages of 45 and 70 years constitute the common demographic affected by the paraneoplastic pemphigus disease; however, the disorder may affect children as well. Europe is the second leading market for the paraneoplastic pemphigus (PNP) disease, propelled by the increasing geriatric population and growing use of tobacco in the region. In 2015, the geriatric population in Europe stood at 129.6 million which is likely to reach 169.1 million and 196.8 million in 2030 and 2050 respectively. The market in Asia Pacific is projected to witness a higher growth rate owing to the rapid surge in population, increasing health care expenditure, favorable health care insurance coverage, and the developing economy of the region. According to Pfizer Inc., 3.6 million males and 4.0 million females in Asia are cancer patients. China alone has 1.6 million male and 1.5 million female cancer survivors. Emerging regions such as Latin America and Middle East & Africa are predicted to create major opportunities for the global paraneoplastic pemphigus (PNP) disease market on account of the growing investment of major market players and increasing private health care insurance coverage here.

Key players operating in this market include F. Hoffmann-La Roche Ltd, Sanofi S.A., Pfizer Inc., Teligent Inc, GlaxoSmithKline LLC, Teva Pharmaceutical Industries, and Novartis International AG.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Cancer Biomarkers Market is Expected to Witness Dynamic Growth in Future!!

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Several players operate in the global cancer biomarkers market, catering to niche segment. The global biomarkers market offers a favorable environment for competitors as there are several unique customer segments within the industry, exhibiting demand for distinct product type. However, as market players target multiple pathways, in the near future the market could witness increased competition. Abbott Laboratories, Merck & Co., Inc., Thermo Fisher Scientific, Inc., Illumina, Inc., and bioMérieux SA are among the leading market players, finds Transparency Market Research (TMR) in a new study.

Considering the dynamic business environment, a majority of the market players are focusing on achieving greater market share via product differentiation. The research and development spending is thus significantly high in the market. Besides this, several companies are aiming at expanding their footprint through acquisitions and disinvestments. As the companies continue spending on product development and technological advancements, consequently the cancer biomarkers market will witness greater opportunities for growth.

According to TMR, the global cancer biomarkers market, which stood at US$10.25 bn in 2016, is expected to reach US$27.63 bn by the end of 2027. If these figures hold true, the global cancer biomarkers market will exhibit a CAGR of 11.8% between 2017 and 2025. By disease indication, the demand for cancer biomarkers was the highest for the treatment of lung cancer, which is likely to hold nearly 25.8% of the market by the end of 2017. Regionally, North America held the dominant share of 42.5% of the global market in 2016.

Rising Funding for Cancer Research to Boost Growth Opportunities

The market is majorly gaining from the rising discretionary funding for cancer research. Governments across most developed countries are engaged in raising funds for cancer research to aid in diagnosis and research. They are also funding clinical trials for breakthroughs in cancer treatment. As their initiatives gain pace, the cancer biomarkers market will witness greater growth opportunities. Also steps taken by the government to spread cancer awareness will help the market gain momentum. In lines with the same, the demand for cancer biomarkers will therefore rise in response to the rising incidence of cancer worldwide.

To gain a stronger foothold, the leading market players are forging strategic collaborations. They are also keen on acquiring established regional players to expand their geographic footprint. Such strategies adopted by companies will have a positive influence on the market. Besides these, growing acceptance of patients towards innovative technologies and tests and novel product launches will enable the market exhibit strong growth during the forecast period.

Lack of Awareness to Act as Major Restraint to Growth

On the downside, the unwillingness of healthy population to participate in clinical research is acting against the market’s growth prospects. While overall, the incidence of cancer cases is surging around the world, but not many of them have access to proper treatment. This is partly due to the lack of participation in clinical trials and unavailability of patient surveillance systems. Given the scenario, low awareness and ambiguity regarding blood tests such as tumor biomarkers are inhibiting the cancer biomarker market’s trajectory. Also the high attrition rate in product development cycle is restricting the market’s growth to an extent.

Nevertheless, with the advent of minimal-invasive diagnostic tests for cancer diagnosis will support the market’s growth in the near future. Minimally invasive diagnosis will provide simple and comparatively less expensive method of detecting cancer. These innovations will bring in fresh opportunities for the market players to capitalize on. Also the market will witness considerable growth opportunities as governments across emerging nations boost their healthcare spending and take steps to deliver healthcare services at par with the international standards.

This review is based on a TMR report, titled “Cancer Biomarkers Market (Test Type – PSA Tests, CTC Tests, AFP Tests, CA Tests, HER2 Tests, BRCA Tests, ALK Tests, CEA Tests, EGFR Mutation Tests, and KRAS Mutation Tests; Disease Indication – Breast Cancer, Lung Cancer, Colorectal Cancer, Melanoma, Blood Cancer, Prostate Cancer, Ovarian Cancer, Stomach Cancer, and Liver Cancer) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 – 2025.”

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Growing Trends in Companion Diagnostic Tests in Oncology Market

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Transparency Market Research (TMR) observes that the degree of competition in the global companion diagnostic tests in oncology market is moderate to high with several manufacturers vying to collaborate with pharmaceutical manufacturers. Furthermore, the growing number of players in the global market with breakthrough technologies are also expected raise the stakes for existing players. The top three players, Illumina, Inc., Abbott Laboratories, and Agilent Technologies, Inc., held a share of 23% in the global market in 2016. These players are expected to focus on product innovation and partnerships to stay of the competition in the coming years.

Companion Diagnostic Testing to be Extensively Used for Detecting Breast Cancer

According to the research report, the global companion diagnostic tests in oncology market is expected to be worth US$13.6 bn by the end of 2025 from US$3.5 bn in 2016. During the forecast period of 2017 and 2025, the global market is projected to rise at a CAGR of 16.8%. Companion diagnostic tests in oncology will be predominantly used for detection of breast cancer. This expected to provide the breast cancer segment a definitive boost in the coming years, helping it rise at a CAGR of 17.0% between 2017 and 2025. From a geographic point of view, North America is expected to remain dominant, accounting for a share of 37.5% by the end of 2025.

The growing demand for personalized healthcare along with targeted therapies have augmented the growth of the global companion diagnostic tests in oncology market. The pharmaceutical industry is gradually moving toward developing specific therapies to treat varying types of chronic diseases and disorders such as cancer. The uptake of biomarkers and companion diagnostic tests have enabled healthcare providers to offer a range of well-suited therapies to the patients, thereby ensuring faster healing time. High prevalence of cancer, increasing risk of cancer, lifestyle changes, and frequent occurrence of diseases such as Hepatitis are expected to drive the global market.

Reduction in Cost of Drug Discovery Augments Demand for Companion Diagnostic Tests in Oncology

The global market is also benefitting from the remarkable reduction of drug discovery costs due to adoption of companion diagnostics. These diagnostics are used in the process of drug discovery as they reduce the time spent in clinical trials by delivery faster results in an efficient and effective manner. This factor is assessed to play an instrumental role in defining the trajectory of the global companion diagnostic tests in oncology market. The growing concerns about unmet medical needs are also expected to drive the demand for companion diagnostic tests in oncology market in the coming years as pharmaceutical companies will focus on research and development to introduce new drugs.

The delayed processes of approvals for targeted therapies are expected to hamper the growth of the global companion diagnostic tests in oncology market. Furthermore, the complication reimbursement scenario has also dissuaded the global market over the past few years. The scattered interests of stakeholders in the global market is also acting as an impediment to the overall market.

This review is based on Transparency Market Research’s report, titled “Companion Diagnostic Tests in Oncology Market (Detection Technique – Protein Detection, DNA Detection (Polymerase Chain Reaction, Next Generation Sequencing, and In Situ Hybridization (Fluorescence In Situ Hybridization, and Chromogenic In Situ Hybridization)); Biomarker – EGFR, BRAF V600E, KRAS, and HER2; Cancer Type – Breast Cancer, Lung Cancer, Colorectal Cancer, Liver Cancer, and Melanoma; End User – Pharmaceutical and Biotechnology Companies, Medical Device Companies, and Research Institutes) – Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 – 2025.”

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Human Microbiome Market: Impact of Key Factors Influencing the Parent Industry

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The global human microbiome market is in a nascent phase, which is attracting a large number of players to foray into this market. Transparency Market Research (TMR) estimates that this, resultantly, is likely to intensify the competition within this market over the coming years. Enterome Biosciences SA, Vedanta Biosciences, Seres Therapeutics, Synthetic Biologics Inc., uBiome Inc., Second Genome, Osel Inc., Rebiotix Inc., Metabiomics Corp., MicroBiome Therapeutics LLC., and AO Biome LLC are among the frontrunners in the arena.

The leading players are focusing towards product innovations and technological advancements to consolidate their position in the global human microbiome market in the near future. “Mergers and acquisition will be other go-to strategies preferred by market participants in order to expand their business,” says the author of the report.

The global market for human microbiome is poised to expand at a noteworthy CAGR of 9.80% between 2020 and 2024, reaching a valuation of US$2.2 bn by 2020. By the end of forecast period, the market is expected to cross the mark of US3.2 bn.

North America to Stay at Forefront of Growth until 2024

Therapeutics and diagnostics are the two primary categories of the global human microbiome market. The market for human microbiome therapeutics is estimated to register a higher CAGR of 9.20% during the forecast period. Geographically, North America will continue to account for the lion’s share in the global market until 2024, thanks to the widening base of venture-capital funded startups. The growth of the region can also be attributed to the presence of a state-of-art medical and healthcare sectors and early adoption of technology.

Increasing Clinical Trials for Gut Health-based Diseases to Drive Human Microbiome Market

High unmet needs coupled with the growing investments by venture capital organizations and angel investors in research and development activities in the field of diagnosis and therapeutics of underrated diseases are providing a fillip to the market. With human microbiome being a novel and highly potent realm, drug manufacturers across the globe are increasing their focus on it, which is translating into the greater capital investments. “Human microbiome is used for early detection and diagnosis of diseases. Moreover, it has been accredited as a new target for drug development,” says a TMR analyst. The rising number of clinical trials for gut health-based diseases is also playing a pivotal role in the growth of the global market.

Dearth of Proper Infrastructure and Skilled Personnel for Research to Hamper Growth Prospects

The increasing collaborations between market players and research institutes are shaping the future of the global human microbiome market. However, several factors are acting as dark spots in the landscape. The dearth of personnel with expertise and lack of proper infrastructure for research, especially in developing countries, are impeding the upward climb of the market. Moreover, human microbiome is still in its initial stages and therefore, there are various uncertainties over its performance. Besides this, stringent government regulations for approval are acting as a bottleneck in the development of the market.

The study presented here is based on a report by Transparency Market Research (TMR), titled “Human Microbiome Market (Indication – Gastrointestinal and Metabolic Disorders, Women’s Health, and Cancer; Technology – 16s rRNA Sequencing and Metagenomic Sequencing; Therapeutic Area – Gastrointestinal Disorders, Metabolic Disorders, Women’s Health, and Skin Disorders) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2018 – 2024.”

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Chronic Kidney Disease Drugs Market: Advancements in Chronic Kidney Disease Drugs to Propel Market

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Global Chronic Kidney Disease Drugs Market: Snapshot

The global market for chronic kidney disease drugs continues to proliferate at a significant pace, driven by the increasing number of chronic kidney disease patients and the growing need of novel treatments to improve patients’ quality of life. The increasing number of elderly people, who are more vulnerable to various diseases due to poor immunity, such as cardiovascular disorders, diabetes, and neurological conditions, is another important factor behind the growth of this market, as, owing to this, the prevalence of these diseases is rising considerably across the world.

Going forward, the market is projected to be propelled substantially in the near future by the technological advancements, leading to the development of a wide array of drugs, which will enable clinicians to provide proper assistance to chronic kidney disease patients. The global chronic kidney disease drugs market stood at US$11.5 bn in 2015. Burgeoning at a CAGR of 3.60% between 2016 and 2024, the market’s opportunity is expected to reach US$15.8 bn by the end of 2024.

Calcium Channel Blockers to Remain Market Leader Supported by Strong Demand

The global market for chronic kidney disease drugs is studied on the basis of a number of parameters, among which the drug class is a prominent one. Based on the drug class, the market is classified primarily into ACE Inhibitors, Angiotensin-II receptor blockers, calcium channel blockers, beta blockers, erythropoiesis-stimulating agents (ESAs), and diuretics.

Calcium channel blockers surfaced as the key drug class in 2015, leading the market with a share of 18.9%. Currently, the main calcium channel blockers utilized across the world are benzothiazepines (diltiazem), phenyl alkyl amines (verapamil), and dihydropiridines (nifedipine and amlodipine).

Hospitals and specialty clinics are the prime end users of chronic kidney disease drugs. The hospitals segment, which is the current market leader, is expected to continue its dominance in this market over the next few years.

Strong Economic Conditions to Prove Favorable for North America Chronic Kidney Disease Drugs Market

The worldwide chronic kidney disease drugs market is stretched across North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America led this market in 2015 with a share of 31.8%. Driven by the strong economic condition of the region and the high acceptance for advanced technology products, the North America chronic kidney disease drugs market is likely to maintain its lead over the forthcoming years. The increasing cases of diabetes and obesity related disorders are also projected to boost this regional market in the near future.

Europe, which was the second leading market for chronic kidney disease drugs across the world in 2015, is likely to present the most attractive growth opportunities to market players in the years to come due to the increasing pool of kidney cancer patients in this region. The high rate of adoption and usage of superior quality treatments for these diseases is also predicted to aid the Europe chronic kidney disease drugs market over the next few years. The significant expansion of the medical and healthcare industry in China, Japan, and Australia is likely to drive the Asia Pacific market for chronic kidney disease drugs in the near future.

Teva Pharmaceutical Industries Ltd., Amgen Inc., AstraZeneca Plc, Pfizer Inc., F. Hoffmann-La Roche Ltd., Sanofi S.A., GlaxoSmithKline Plc, AbbVie Inc., Kissei Pharmaceutical Co. Ltd., and Keryx Biopharmaceuticals Inc. are some of the leading makers of drugs for the treatment of chronic kidney diseases across the world.

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Gastrointestinal Drugs Market 2024: Business Development Analysis

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The global gastrointestinal drugs market is consolidated with the top three players accounting for a whopping 61% of the market collectively in 2016. These three players are: Valeant Pharmaceuticals Inc., Janssen Biotech Inc., and Takeda Pharmaceutical. While the market is moderately competitive at present, future holds much competitiveness among players and thus, the degree of competition is expected to be increase in the forecast period, states a report by Transparency Market Research (TMR). Some of the other players in the market are: Bayer AG, Boehringer Ingelheim GmbH Sanofi, Allergan Plc, AstraZeneca, GlaxoSmithKline, Allergan Plc., and Abbott Laboratories.

As per the research report, the global gastrointestinal drugs market is anticipated to be worth US$61.1 bn by 2024. By drug class, acid neutralizers segment not led in the past, but is also expected to remain in the leading position in the coming years. This is because, acid neutralizers are cost effective and also because the increasing prevalence of gastroesophageal reflux disease (GERD), will drive this segment.

Asia Pacific to Emerge Most Lucrative in Gastrointestinal Drugs Market

On the basis of geography, the global gastrointestinal drugs market is expected to be led by North America. Favorable reimbursement policies, and increasing geriatric population, who are more prone to gastrointestinal disorders, will drive the region’s growth during the forecast period from 2016 to 2024. North America held 41% of the market in 2016. Europe has also been witnessing healthy growth and is anticipated to continue being an attractive region for gastrointestinal drugs market. “The emergence of biosimilars for treating inflammatory bowel diseases will also be a key growth driver for the market in Europe,” says a TMR analyst. However, Asia Pacific is estimated to be the region with maximum opportunities for growth in the coming years. The growing investments and funding in the field of life science research and advanced therapies for the treatment of gastrointestinal diseases in developing nations such as China and India will fuel the growth of the Asia Pacific market.

Rising Awareness about Availability of Treatment Options Driving Demand for Gastrointestinal Drugs

A report published by World Gastroenterology Organization states that around 15 to 25% of the people across the globe are suffering from gastro-esophageal reflux disease (GERD). This is positively impacting the demand for gastrointestinal drugs. The growing awareness about the disease and the increasing availability of treatment options is boosting the growth of the market. The growing investments in research and development activities for innovation of new drugs will further the growth of the market.

Unavailability of Permanent Cure to Pose a Challenge for Market Players

The etiology of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) remains a mystery and this is expected to hamper the growth of the global gastrointestinal drugs market. The lack of permanent cure for gastrointestinal diseases will also act as a challenge for market players. On the positive side, the consistent technological advancements in the treatment therapies of gastrointestinal diseases are projected to reduce the impact of the aforementioned restraints, states a TMR analyst.

The information presented in this review is based on a Transparency Market Research report, titled, “Gastrointestinal Drugs Market (Drug Class – Acid Neutralizers (Antacids, H2 Antagonists, and Proton Pump Inhibitors), Antidiarrheal and Laxatives, Antiemetic and Antinauseants, Anti-inflammatory Drugs, Biologics, and Antispasmodic; Route of Administration – Oral, Parenteral and Rectal; Disorder Type – Gastro-esophageal Reflux Disease, Inflammatory Bowel Disease, and Irritable Bowel Syndrome; Distribution Channel – Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 – 2024.”

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U.S. Knee Implant Market: Worldwide Market Shares, Strategies, and Forecasts 2016 to 2024

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In 2015, nearly 85% of the U.S. knee implant market was taken up by a consolidated competitive segment of popular players, which included Stryker Corp, Smith & Nephew, Zimmer Biomet Holdings, Inc., and Johnson & Johnson. According to Transparency Market Research, this consolidated market scenario is expected to remain the same over the coming years due to a strict regulatory framework, and the high costs of development and implementation.

The leaders in the U.S. knee implant market are known to hold a highly detailed product portfolio in not just knee replacement, but in the healthcare and medical devices industries as a whole. This allows them to diversify their profile through cross-selling and thereby maintaining a higher demand and loyalty rate. The TMR report states that the U.S. knee implant market is expected to reach US$7.0 bn by the end of 2024, after calculated to be expanding at a CAGR of 5.3% in terms of market value, within a forecast period from 2016 to 2024. The market was also calculated to have reached US$4.62 bn at the end of 2016, owing to its several drivers at the time.

Knee Replacement Demands Soar as Geriatric Population on the Rise

“The primary patient pool that shows a commonly high demand for knee replacement procedures is the geriatric demographic. The knees are often vulnerable to excessive wear and therefore become highly susceptible to needing replacement. This fact, compounded by the growing population of the elderly in the U.S., is creating a massive surge in the overall demand experienced by the U.S. knee implant market,” states a TMR analyst.

Additional factors that are creating a heightened need for knee replacements are accidents and other injuries that damage the knees beyond repair, and the growing count of patients with chronic diseases that lead to increased joint tension and wear. This includes the growing number of patients suffering from chronic rheumatic conditions, as well as the increasing count of obese people in the U.S. Further boost to the U.S. knee implant market is given by the introduction of advanced knee support devices that are currently generating a very high demand volume.

Midwest U.S. Shows Leading Demand for Knee Implants

Within the U.S. knee implant market, the Midwest region has been known to show a high demand for knee implants over the recent past. This trend is likely to continue over the coming years. This is due to the relatively greater ability of the region in delivering advanced medical support and using advanced implementations of knee implants. This region also holds a larger pool of manufacturers from the U.S. knee implant market.

However, the U.S. knee implant market is currently being restrained by the increasingly stringent government regulations against the use of certain materials, or the use of certain manufacturing procedures, for replacement knee products. The FDA has set up extremely strict mandates that players in the U.S. knee implant market need to follow, and this has been implied through the steady rate of product recalls made by the FDA. At the same time, the U.S. knee implant market is also receiving a setback from the growing popularity of non-surgical alternatives that are being sought by an increasing number of patients.

“The future of the U.S. knee implant market is likely to lie in the growing developments on the scope of customization of knee implants and building support systems for them. One of the more invested portals to accomplish this is the booming 3D printing industry, which can be feasible for the manufacture of custom knee implants,” adds the analyst.

The information presented in this review is based on a Transparency Market Research report, titled, “Knee Implant Market (Product Type – Total Knee Replacement Implant, Partial Knee Replacement Implants, and Revision Knee Replacement Implants; Material – Stainless Steel, Cobalt Chromium Alloys, Titanium and Titanium Alloys, Polyethylene, Ceramics, Uncemented implants, Tantalum, and Zirconium; End User – Hospitals, Specialized Orthopedic Clinics, and Ambulatory Surgery Centers – U.S. Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 – 2024.”

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Transparency Market Research

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Tel: +1-518-618-1030

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